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Symbol Name ID |
Wfs1
wolframin ER transmembrane glycoprotein MGI:1328355 |
| Darker colors indicate more annotations |
| Human Phenotypes | Hypogonadism |
Male hypogonadism |
Testicular atrophy |
| Disease(s) Associated with WFS1 | |||
| optic atrophy | |||
| Wolfram syndrome | |||
| Wolfram syndrome 1 |
| Mouse Phenotypes | abnormal sperm flagellum morphology |
abnormal sperm head morphology |
abnormal spermatogonia morphology |
decreased male germ cell number |
increased sperm motility |
abnormal seminiferous tubule morphology |
abnormal seminiferous tubule epithelium morphology |
decreased Sertoli cell number |
reduced male fertility |
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| Availability | Mouse Genotype | |||||||||
| Wfs1tm1Koks/Wfs1tm1Koks | ||||||||||
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 04/30/2024 MGI 6.23 |
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